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KMID : 1130620120080030184
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Journal of Clinical Neurology
2012 Volume.8 No. 3 p.184 ~ p.189
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Anorectal Manometric Dysfunctions in Newly Diagnosed, Early-Stage Parkinson’s Disease*
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Sung Hye-Young
Choi Myung-Gyu
Kim Yeong-In
Lee Kwang-Soo
Kim Joong-Seok
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Abstract
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Background and Purpose: Anorectal dysmotility is common in advanced Parkinson’s disease (PD), but there have been few evaluations in newly diagnosed PD patients.
Methods: We conducted anorectal manometric evaluations in 19 newly diagnosed, drug-naive, early-stage PD patients. All of the PD patients were questioned regarding the presence of anorectal symptoms.
Results: Anorectal manometry was abnormal in 12 of the 19 patients. These abnormalities were more common in patients with more severe anorectal symptoms, as measured using a self-reported scale. However, more than 40% of patients with no or minimal symptoms also exhibited manometric abnormalities.
Conclusions: These results suggest that anorectal dysmotility manifests in many early-stage PD patients, which this represent evidence for the involvement of neuronal structures in such nonmotor manifestations in PD.
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KEYWORD
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Parkinson’s disease, anorectal dysfunction, manometry
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